The Hidden Link Between Nutrient Deficiencies and Migraines

Why Nutrients Matter

Your brain is an energy-demanding organ. It relies on a delicate balance of nutrients to regulate nerve signals, blood flow, inflammation, and mitochondrial function. When even one key nutrient is out of balance, the neurological system can become more sensitive—leading to increased susceptibility to migraines.

Let’s explore the most common deficiencies we see in migraine patients and how addressing them can lead to lasting relief.

1. Magnesium: The Migraine Mineral

Magnesium plays a critical role in neuromuscular conduction and vascular tone—two processes often implicated in migraine attacks. Deficiency in magnesium can lead to heightened nerve excitability and blood vessel constriction, common triggers in migraine episodes.

Common signs of deficiency: muscle cramps, anxiety, insomnia, and sensitivity to light/sound.

Functional medicine tip: We often recommend chelated magnesium glycinate or magnesium threonate for better absorption and brain support.

2. Riboflavin (Vitamin B2): Energy for the Brain

Riboflavin supports mitochondrial energy production. Since migraines have been linked to mitochondrial dysfunction in the brain, a deficiency in B2 can impair energy output, leaving brain cells more vulnerable to stress.

Clinical insight: Studies have shown that 400 mg/day of riboflavin can significantly reduce migraine frequency in some individuals.

3. CoQ10: Fueling the Mitochondria

Coenzyme Q10 (CoQ10) is another vital nutrient for mitochondrial function. It acts as an antioxidant and supports the production of cellular energy. Low CoQ10 levels have been associated with increased migraine frequency and severity.

Pro tip: We recommend ubiquinol, the active form of CoQ10, for better bioavailability, especially in patients with fatigue and cardiovascular concerns.

4. Vitamin D: Immune and Pain Regulation

Low vitamin D has been linked to chronic inflammation and dysregulation of pain pathways. Since migraines are influenced by inflammation and immune triggers, correcting a deficiency can be transformative.

Did you know? Many of our patients with autoimmune components or mood fluctuations also have low vitamin D—and see improvements in both areas after supplementation.

5. B Vitamins: Nervous System Support

Vitamins B6, B9 (folate), and B12 are essential for neurotransmitter synthesis and methylation pathways. Imbalances or genetic variants (such as MTHFR mutations) can impair detoxification and brain chemistry regulation, potentially contributing to migraine susceptibility.

Functional approach: We use methylated forms of B vitamins to support individualized detox and neurotransmitter balance.

Your Body Is Talking—Are You Listening?

If you’ve been chasing symptoms with pain relievers or even prescriptions that offer temporary relief, it may be time to dig deeper. At NeuroWorks Wellness Center, we specialize in identifying and addressing the root causes of neurological dysfunction—including nutrient imbalances that traditional care often overlooks.

Through advanced lab testing, customized supplement protocols, and functional nutrition strategies, we help you retrain your brain toward healing—not just symptom suppression.

Ready to get to the root of your migraines?

Schedule your virtual consultation today and let’s begin your journey toward clarity and comfort.

📞 (713)355-9415

🌐 www.NeuroWorksWellness.com📍

Serving clients virtually across Texas and beyond